Publications

For a full list of my publications see my Google Scholar page

trachea-esophageal development

2024

Nicole A. Edwards, Scott A. Rankin, Adhish Kashyap, Alissa Warren, Zachary N. Agricola, Alan P. Kenny, Matthew J. Kofron, Yufeng Shen, Wendy K. Chung, Aaron M. Zorn. Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in trachea-esophageal morphogenesis. bioRxiv https://doi.org/10.1101/2023.10.11.561909

2022

Guojie Zhong, Priyanka Ahimaz, Nicole A Edwards, Jacob J Hagen, Christophe Faure, Qiao Lu, Paul Kingma, William Middlesworth, Julie Khlevner, Mahmoud El Fiky, David Schindel, Elizabeth Fialkowski, Adhish Kashyap, Sophia Forlenza, Alan P Kenny, Aaron M Zorn, Yufeng Shen, Wendy K Chung. Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas. HGG Advances 3(3):100107 https://doi.org/10.1016/j.xhgg.2022.100107

2019

Talia Nasr, Pamela Mancini, Scott A Rankin, Nicole A Edwards, Alan P Kenny, Jessica L Kinney, Keziah Daniels, Jon Vardanyan, Lu Han, Stephen L Trisno, Sang-Wook Cha, James M Wells, Matthew J Kofron, Aaron M Zorn. Endosome-mediated epithelial remodeling downstream of Hedgehog-Gli is required for tracheoesophageal separation. Developmental Cell 51(6): 665-674 https://doi.org/10.1016/j.devcel.2019.11.003

review papers

Nicole A Edwards, Vered Shacham-Silverberg, Leelah Weitz, Paul S Kingma, Yufeng Shen, James M Wells, Wendy K Chung, Aaron M Zorn. Developmental basis of trachea-esophageal birth defects (2021) Developmental Biology 477:85-97 https://doi.org/10.1016/j.ydbio.2021.05.015

Nicole A Edwards, Aaron M Zorn. Modeling endoderm development and disease in Xenopus (2021) Current Topics in Developmental Biology 145:61-90 https://doi.org/10.1016/bs.ctdb.2021.01.001

EARLY mouse EMBRYO DEVELOPMENT

Nicole A Edwards, Andrew J Watson, Dean H Betts. Knockdown of p66Shc alters lineage-associated transcription factor expression in mouse blastocysts (2018) Stem Cells and Development 27(21):1479-1493 https://doi.org/10.1089/scd.2018.0131

NA Edwards, AJ Watson, DH Betts. P66Shc, a key regulator of metabolism and mitochondrial ROS production, is dysregulated by mouse embryo culture (2016) Molecular Human Reproduction 22(9):634-647 https://doi.org/10.1093/molehr/gaw043

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